The Bills enter as 64% favorites after a 5-1 start and two-game winning streak, while the Ravens are 4-3 and have lost their last two games including a 35-13 defeat to Cincinnati. Multiple analytical models including numberFire (69.1%) and Opta's Supercomputer (62.5%) project Buffalo to win, with the Bills' league-leading offensive efficiency and Ravens' injury concerns around QB Lamar Jackson supporting the consensus.